Intrahepatic Cholangiocarcinoma Market to Grow Rapidly During the Study Period (2019-2032), Examines DelveInsight | Key Players – Virogin Biotech, Syndax, Delcath Systems, AstraZeneca, Amgen, Jazz, BeiGene

The dynamics of the intrahepatic cholangiocarcinoma market are anticipated to change in the coming years owing to the improvement in the diagnosis methodologies, rising awareness of the disease, incremental healthcare spending worldwide, and the expected launch of emerging therapies

 LAS VEGAS, Sept. 20, 2023 /PRNewswire/ — DelveInsight’s Intrahepatic Cholangiocarcinoma Market Insights report includes a comprehensive understanding of current treatment practices, intrahepatic cholangiocarcinoma emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].

Key Takeaways from the Intrahepatic Cholangiocarcinoma Market Report

  • As per DelveInsight analysis, the intrahepatic cholangiocarcinoma market is expected to grow positively at a significant CAGR during the study period (2019–2032).
  • In the Western world, the incidence of intrahepatic cholangiocarcinoma is 1 to 2 per 100,000. Intrahepatic cholangiocarcinoma is the second most prevalent liver cancer, accounting for 3% of all gastrointestinal cancer cases. 
  • Leading intrahepatic cholangiocarcinoma companies such as Virogin Biotech Ltd., Syndax Pharmaceuticals, Delcath Systems Inc., TriSalus Life Sciences, Inc., AstraZeneca, Relay Therapeutics, Inc., Kinnate Biopharma, Elucida Oncology, Lisata Therapeutics, Inc., Amgen, Jazz Pharmaceuticals, BeiGene, Ltd., and others are developing novel intrahepatic cholangiocarcinoma drugs that can be available in the intrahepatic cholangiocarcinoma market in the coming years.
  • Some key therapies for intrahepatic cholangiocarcinoma treatment include VG161, SNDX-6352, Cisplatin and Gemcitabine, SD-101, Y-90 With Durvalumab/Gem/Cis, RLY-4008, KIN-3248, ELU001, LSTA1, Bemarituzumab, ZW25 (Zanidatamab), and others.

Discover which therapies are expected to grab the major intrahepatic cholangiocarcinoma market share @ Intrahepatic Cholangiocarcinoma Market Report

Intrahepatic Cholangiocarcinoma Overview

Intrahepatic cholangiocarcinoma, a rare and aggressive form of cancer, originates in the bile ducts within the liver. While the exact causes are not always clear, certain risk factors have been identified. Chronic inflammation of the bile ducts, often due to conditions like primary sclerosing cholangitis or chronic liver infections, can increase the risk. Additionally, exposure to certain chemicals and toxins may play a role in the development of this cancer. Symptoms of intrahepatic cholangiocarcinoma can be subtle and nonspecific, which makes early diagnosis challenging. Common symptoms include jaundice, abdominal pain, unexplained weight loss, and fatigue. Some patients may also experience itching, dark urine, or pale-colored stools. Diagnosing intrahepatic cholangiocarcinoma typically involves a combination of imaging tests, such as CT scans, MRI scans, and ultrasound, to visualize the tumor within the liver. A biopsy may be necessary to confirm the diagnosis, where a small sample of tissue is extracted and examined under a microscope.

Intrahepatic Cholangiocarcinoma Epidemiology Segmentation

The intrahepatic cholangiocarcinoma epidemiology section provides insights into the historical and current intrahepatic cholangiocarcinoma patient pool and forecasted trends for individual seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. 

The disease epidemiology covered in the report provides historical as well as forecasted intrahepatic cholangiocarcinoma epidemiology scenarios in the 7MM covering the United States, EU4 countries (Germany, Spain, Italy, France), the United Kingdom, and Japan from 2019 to 2032.

Intrahepatic Cholangiocarcinoma Treatment Market 

Treatment for intrahepatic cholangiocarcinoma depends on several factors, including the stage of the cancer, the patient’s overall health, and individual preferences. Typically, intrahepatic cholangiocarcinoma treatment options include surgery, liver transplantation, chemotherapy, radiation therapy, and targeted therapies. Surgery, such as a partial hepatectomy, is often the preferred treatment when the cancer is detected early and is localized to a specific area of the liver. Liver transplantation may be an option for some patients with advanced intrahepatic cholangiocarcinoma. Chemotherapy, often in combination with targeted therapies, is used to shrink tumors before surgery or to treat cancer that has spread beyond the liver. Radiation therapy may also be employed to target and destroy cancer cells. Additionally, advancements in immunotherapy and clinical trials offer hope for novel treatment avenues. The intrahepatic cholangiocarcinoma treatment necessitates a personalized approach, with healthcare teams comprising oncologists, surgeons, radiologists, and other specialists collaborating closely to determine the most effective strategy for each patient. Early diagnosis and timely intervention remain pivotal in improving prognosis and overall outcomes for individuals with this challenging form of liver cancer.

To know more about intrahepatic cholangiocarcinoma treatment, visit @ Intrahepatic Cholangiocarcinoma Treatment Drugs 

Key Intrahepatic Cholangiocarcinoma Therapies and Companies

  • VG161: Virogin Biotech Ltd.
  • SNDX-6352: Syndax Pharmaceuticals
  • Cisplatin and Gemcitabine: Delcath Systems Inc.
  • SD-101: TriSalus Life Sciences, Inc.
  • Y-90 With Durvalumab/Gem/Cis: AstraZeneca
  •  RLY-4008: Relay Therapeutics, Inc.
  • KIN-3248: Kinnate Biopharma
  • ELU001: Elucida Oncology
  • LSTA1: Lisata Therapeutics, Inc.
  • Bemarituzumab: Amgen
  • ZW25 (Zanidatamab): Jazz Pharmaceuticals/BeiGene, Ltd.

Learn more about the FDA-approved drugs for intrahepatic cholangiocarcinoma @ Drugs for Intrahepatic Cholangiocarcinoma Treatment 

Intrahepatic Cholangiocarcinoma Market Dynamics

The intrahepatic cholangiocarcinoma market dynamics have been undergoing significant changes in recent years. The growing awareness and improved diagnostic techniques have led to an earlier detection of ICC cases. This, coupled with advancements in treatment modalities such as surgical resection, liver transplantation, and targeted therapies, has expanded the range of therapeutic options available to patients. Additionally, ongoing research into immunotherapies and intrahepatic cholangiocarcinoma is providing new hope for more effective treatments. As a result, the intrahepatic cholangiocarcinoma market is witnessing increased investments in research and development, heightened competition among pharmaceutical companies, and a focus on developing innovative therapies tailored to the specific molecular characteristics of individual patients. These evolving dynamics are poised to transform the landscape of intrahepatic cholangiocarcinoma treatment, offering improved prospects for patients facing this challenging disease.

Intrahepatic cholangiocarcinoma faces several notable barriers within its market dynamics. Firstly, the rarity of intrahepatic cholangiocarcinoma makes it challenging to conduct large-scale clinical trials and gather comprehensive data, hindering the development of evidence-based treatment approaches. Moreover, the often late-stage diagnosis of intrahepatic cholangiocarcinoma presents a significant hurdle, as advanced disease is more difficult to treat effectively.

Additionally, the high cost of cutting-edge therapies, such as targeted treatments and immunotherapies, poses financial barriers to access for many patients and healthcare systems. These treatments may not be affordable or accessible to all, limiting their widespread adoption. Regulatory challenges, including the approval process for novel therapies, can also slow down the introduction of innovative treatments into the market. Furthermore, intrahepatic cholangiocarcinoma‘s heterogeneity at the molecular level presents a complex challenge. Tailoring treatments to each patient’s specific genetic profile is promising but also demands advanced diagnostic capabilities and a deeper understanding of the disease’s biology.

Report Metrics


Study Period



7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan]

Key Intrahepatic Cholangiocarcinoma Companies

Virogin Biotech Ltd., Syndax Pharmaceuticals, Delcath Systems Inc., TriSalus Life Sciences, Inc., AstraZeneca, Relay Therapeutics, Inc., Kinnate Biopharma, Elucida Oncology, Lisata Therapeutics, Inc., Amgen, Jazz Pharmaceuticals, BeiGene, Ltd., and others

Key Intrahepatic Cholangiocarcinoma Therapies

VG161, SNDX-6352, Cisplatin and Gemcitabine, SD-101, Y-90 With Durvalumab/Gem/Cis, RLY-4008, KIN-3248, ELU001, LSTA1, Bemarituzumab, ZW25 (Zanidatamab), and others

Scope of the Intrahepatic Cholangiocarcinoma Market Report

  • Therapeutic Assessment: Intrahepatic Cholangiocarcinoma current marketed and emerging therapies
  • Intrahepatic Cholangiocarcinoma Market Dynamics: Conjoint Analysis of Emerging Intrahepatic Cholangiocarcinoma Drugs
  • Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
  • Unmet Needs, KOL’s views, Analyst’s views, Intrahepatic Cholangiocarcinoma Market Access and Reimbursement

Discover more about intrahepatic cholangiocarcinoma drugs in development @ Intrahepatic Cholangiocarcinoma Clinical Trials

Table of Contents


Intrahepatic Cholangiocarcinoma Market Key Insights


Intrahepatic Cholangiocarcinoma Market Report Introduction


Intrahepatic Cholangiocarcinoma Market Overview at a Glance


Intrahepatic Cholangiocarcinoma Market Executive Summary


Disease Background and Overview


Intrahepatic Cholangiocarcinoma Treatment and Management


Intrahepatic Cholangiocarcinoma Epidemiology and Patient Population


Patient Journey


Intrahepatic Cholangiocarcinoma Marketed Drugs


Intrahepatic Cholangiocarcinoma Emerging Drugs


Seven Major Intrahepatic Cholangiocarcinoma Market Analysis


Intrahepatic Cholangiocarcinoma Market Outlook


Potential of Current and Emerging Therapies


KOL Views


Unmet Needs


SWOT Analysis




DelveInsight Capabilities




About DelveInsight

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SOURCE DelveInsight Business Research, LLP